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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RHOB
All Species:
9.09
Human Site:
T129
Identified Species:
18.18
UniProt:
P62745
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.45
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P62745
NP_004031.1
196
22123
T129
R
S
D
E
H
V
R
T
E
L
A
R
M
K
Q
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_540101
444
48660
T377
R
S
D
E
H
V
R
T
E
L
A
R
M
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9QUI0
193
21764
R129
R
N
D
E
H
T
R
R
E
L
A
K
M
K
Q
Rat
Rattus norvegicus
P62747
196
22105
T129
R
S
D
E
H
V
R
T
E
L
A
R
M
K
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509808
196
21931
A129
R
H
D
E
H
V
R
A
E
L
A
R
L
K
Q
Chicken
Gallus gallus
Q9PSX7
193
21955
R129
R
N
D
E
H
T
R
R
E
L
A
K
M
K
Q
Frog
Xenopus laevis
NP_001089930
196
22122
N129
R
N
D
E
H
V
R
N
E
L
A
R
M
K
Q
Zebra Danio
Brachydanio rerio
NP_998302
193
21875
R129
R
N
D
E
H
T
R
R
E
L
Q
K
M
K
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48148
192
21705
R129
R
N
D
P
N
T
I
R
D
L
A
K
M
K
Q
Honey Bee
Apis mellifera
XP_623225
192
21691
K129
R
N
D
P
N
T
I
K
E
L
S
K
M
K
Q
Nematode Worm
Caenorhab. elegans
Q22038
192
21617
R129
R
S
D
P
Q
T
V
R
E
L
A
K
M
K
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P06780
209
23134
E134
R
N
D
P
Q
T
I
E
Q
L
R
Q
E
G
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
43.9
N.A.
83.1
100
N.A.
91.8
82.6
90.3
83.1
N.A.
80
81.1
78.5
N.A.
Protein Similarity:
100
N.A.
N.A.
44.1
N.A.
89.8
100
N.A.
96.4
89.2
96.4
89.2
N.A.
87.7
89.8
88.2
N.A.
P-Site Identity:
100
N.A.
N.A.
100
N.A.
73.3
100
N.A.
80
73.3
86.6
66.6
N.A.
46.6
46.6
60
N.A.
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
86.6
100
N.A.
86.6
86.6
93.3
80
N.A.
73.3
73.3
66.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
61.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
75.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
9
0
0
75
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
100
0
0
0
0
0
9
0
0
0
0
0
0
% D
% Glu:
0
0
0
67
0
0
0
9
84
0
0
0
9
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% G
% His:
0
9
0
0
67
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
25
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
9
0
0
0
50
0
92
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
100
0
0
9
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
84
0
0
% M
% Asn:
0
59
0
0
17
0
0
9
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
34
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
17
0
0
0
9
0
9
9
0
0
100
% Q
% Arg:
100
0
0
0
0
0
67
42
0
0
9
42
0
0
0
% R
% Ser:
0
34
0
0
0
0
0
0
0
0
9
0
0
0
0
% S
% Thr:
0
0
0
0
0
59
0
25
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
42
9
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _